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NSC 33994

SKU: orb1704278

Description

NSC 33994 is a potent and selective JAK2 inhibitor with an IC50 of 60 nM, demonstrating no activity against Src or TYK2 at 25 µM. This small molecule is a valuable research tool for studying JAK-STAT signaling in hematological malignancies and inflammatory diseases in both cellular and animal models.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number82058-16-0
MW438.65
FormulaC28H42N2O2
SMILESCCN(CC)Cc1cc(ccc1O)C(\CC)=C(/CC)c1ccc(O)c(CN(CC)CC)c1
TargetJAK,Autophagy,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

NSC 33994 (orb1704278)

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