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NSC33994

SKU: orb1704278

Description

NSC 33994 is a potent and selective JAK2 inhibitor with an IC50 of 60 nM, demonstrating no activity against Src or TYK2 at 25 µM. This small molecule is a valuable research tool for studying JAK-STAT signaling in hematological malignancies and inflammatory diseases in both cellular and animal models.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Neuroscience, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number82058-16-0
MW436.65
Purity>98%
FormulaC28H42N2O2
SMILESCCN(CC)Cc1cc(ccc1O)C(\CC)=C(/CC)c1ccc(O)c(CN(CC)CC)c1
TargetKinase
SolubilitySoluble in DMSO (up to 2 mg/ml with warming) or in Ethanol (up to 4 mg/ml with warming).

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

G6
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

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5 mg
$ 220.00
25 mg
$ 530.00
DispatchUsually dispatched within 6-8 weeks
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