NVP-BSK805 2HCl (1092499-93-8(free base))

SKU: orb1300895

Description

NVP-BSK805 2HCl (1092499-93-8 free base) is a potent, ATP-competitive JAK2 inhibitor with an IC50 of 0.5 nM, demonstrating >20-fold selectivity over JAK1, JAK3, and TYK2. It is widely used in research to investigate JAK2-dependent signaling in cellular assays and hematological malignancy models.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

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Key Properties

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Target	JAK,Tyrosine Kinases
Molecular Weight	563.47
Purity	98.75%
Formula	C₂₇H₂₈F₂N₆O·2HCl
SMILES	Cl.Cl.Fc1cc(cc(F)c1CN1CCOCC1)-c1cccc2ncc(nc12)-c1cnn(c1)C1CCNCC1

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Tyrosine Kinases, TyrosineKinases, Tyk2, BSK 805, BSK805, BSK-805, NVP BSK805 2HCl (1092499 93 8(free base)), NVP-BSK 805, NVP-BSK 805 Dihydrochloride, NVP-BSK805, NVP-BSK-805, NVP-BSK805 (dihydrochloride), NVPBSK805 2HCl (1092499938(free base)), NVP-BSK-805 2HCl (1092499-93-8(free base)), NVP-BSK805 2HCl (1092499-93-8(free base)), NVP-BSK805 dihydrochloride, NVP-BSK805 Dihydrochloride, NVP-BSK-805 Dihydrochloride, NVP-BSK805 2HCl (1092499-93-8 free base), JAK3, JAK2, JAK1

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Compound Identifiers

PubChem CID

57339395 ↗

Key Properties

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No computed properties available.

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