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NVS-STG2

SKU: orb2564731

Description

NVS-STG2 is a small molecule STING agonist that functions as molecular glue, promoting oligomerization of human STING by binding between transmembrane domains of adjacent dimers. It potently activates STING-mediated immune responses in vitro and demonstrates antitumor efficacy in hSTING knock-in mouse models.

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

CAS Number3030588-01-0
MW427.5
Purity>98%
FormulaC25H33NO5
SMILESO=C(O)C1=CC=C(NCC2=CC=C(C=C2)C3(OCC(C)(C)CO3)C(C)(C)C)C(OC)=C1
TargetMolecular glue
SolubilitySoluble in DMSO (up to 40 mg/ml)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information

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5 mg
$ 210.00
25 mg
$ 430.00
DispatchUsually dispatched within 5-10 working days
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