Cart summary

You have no items in your shopping cart.

ODN 1668

SKU: orb1982511

Description

ODN 1668 is a Class B CpG oligodeoxynucleotide featuring a phosphorothioate backbone that acts as a potent TLR9 agonist. It stimulates IgM production and enhances antimicrobial immunity through CaTLR9-dependent signaling, making it a valuable tool for immunology research in both cellular assays and animal infection models.

Research Area

Immunology & Inflammation, Infectious Disease & Virology

Images & Validation

Key Properties

CAS Number1186063-66-0
MW6364.1
TargetAntibacterial,TLR
SolubilityH2O:20 mg/mL (3.14 mM)

Bioactivity

In Vivo
Treatment of male Wistar rats (175-200 g) with ODN 1668 (1, 5 mg/kg, intraperitoneal and subcutaneous) induced moderate fever and anorexia, and induced a significant increase in IL-6.
In Vitro
Treatment of mouse bone marrow-derived macrophages with ODN 1668 (6-60 µg/mL, 12-72 hours) increased the production of S100A8/A9, IL-6, and β-galactosidase. Treatment of anti-CD3-treated CD8+ T cells with ODN 1668 (0.3-3.0 μM, 4 days) promoted cell growth in a dose-dependent manner. Treatment of head kidney lymphocytes with ODN 1668 (0.25-32 μg/mL, 12 hours) promoted the proliferation of head kidney lymphocytes and enhanced the expression of immune genes.

Storage & Handling

Storagestore under nitrogen,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

ODN1668

Similar Products

Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

ODN 1668 (orb1982511)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
¥ 2,210.00
5 mg
¥ 4,030.00
10 mg
¥ 5,980.00
25 mg
¥ 9,490.00
50 mg
¥ 13,000.00
100 mg
¥ 17,160.00
200 mg
¥ 23,010.00
DispatchUsually dispatched within 5-10 working days
Bulk Enquiry