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Osimertinib dimer

SKU: orb3135414

Description

Osimertinibdimer is the dimer of Osimertinib. Osimertinib (AZD9291) is a covalent, orally active, irreversible, and mutation-selective EGFR inhibitor, effectively suppressing L858R (IC50=12 nM) and L858R/T790M (IC50=1 nM) EGFR. It addresses resistance to EGFR inhibitors mediated by the T790M mutation in lung cancer.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2564638-97-5
MW1000.22
FormulaC56H67N14O4
SMILESO=C(C=C)NC1=CC(NC=2N=CC=C(N2)C3=CN(C=4C=CC=CC34)C)=C(OC)C=C1N(C)CC[N+](C)(C)CCC(=O)NC5=CC(NC=6N=CC=C(N6)C7=CN(C=8C=CC=CC78)C)=C(OC)C=C5N(C)CCN(C)C
TargetOthers

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information