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Others Antibody

SKU: orb3131435

Description

Atigotatug (FUT8-KO) is a monoclonal antibody expressed in CHO cells, where the fucosyltransferase 8 gene (FUT8) has been knocked out. The absence of fucose enhances the antibody's ADCC effect. It targets the fucosylated ganglioside GM1 (fuc-GM1) and is an IgG1κ type humanized antibody. Atigotatug can induce immune-mediated tumor cell death, such as in small-cell lung cancer.

Images & Validation

Key Properties

Antibody TypeInhibitor Antibody
ClonalityMonoclonal
TargetOthers
ConjugationUnconjugated

Storage & Handling

StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Others Antibody (orb3131435)

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