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PAR4 antagonist 4

SKU: orb3134160

Description

PAR4 antagonist4 (Compound 37) is a selective antagonist of protease-activated receptor 4 (PAR4). It exhibits antiplatelet activity with an IC50 of 14.2 nM. Moreover, PAR4 antagonist3 enhances metabolic stability in human liver microsomes, showing a half-life (T1/2) of 42.5 minutes.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number3057206-41-1
MW453.44
FormulaC22H16FN3O5S
SMILESFC1=CC=C(OCC2OC=3C=CC=4C=C(OC4C3OC2)C=5N=C6SC(=NN6C5)OC)C=C1
TargetProtease-activated Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information