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PHA 568487 free base

SKU: orb1305714

Description

PHA 568487 is a quinuclidine-based α7 nicotinic acetylcholine receptor agonist. Its design aimed to reduce metabolic bioactivation and improve in vivo tolerability of the core scaffold. This compound is used in neuroscience research to study α7 nAChR function in vitro and in vivo models.

Research Area

Metabolism Research, Neuroscience

Images & Validation

Key Properties

CAS Number527680-56-4
MW288.34
Purity99.00% (May vary between batches)
FormulaC16H20N2O3
SMILESO=C(N[C@H]1CN2CCC1CC2)c1ccc2OCCOc2c1
TargetAChR
SolubilityH2O:< 40.44 mg/mL (100 mM);DMSO:30 mg/mL (104.04 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.94 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

ischemic, middle, macrophage, occlusion, nicotinic, memory, fracture, cerebral, artery, acetylcholine, α7 nAChR, polarization, Post-stroke, PHA568487, PHA-568487, PHA 568487 free base, PHA 568487
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

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10 mg
$ 80.00
25 mg
$ 110.00
50 mg
$ 180.00
100 mg
$ 280.00
200 mg
$ 380.00
DispatchUsually dispatched within 3-5 working days
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