Phospho-MSK1 (Thr581) (A5) rabbit mAb PE conjugate Antibody

SKU: orb1946221

Description

MSK1 (mitogen and stress activated protein kinase 1, phospho MSK1) is activated by Erk in response to growth factors and by and p38 in response to cellular stress (1). MSK1 is similar to RSK1 in that it has two kinase domains and a connecting regulatory linker region (2). S364/S381 phosphorylation activates RSK1 (3), which is analogous to residues S360 and S376 of MSK1, which may be important for phospho MSK1 activity.

Images & Validation

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Tested Applications	FC
Dilution range	For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells or 5 µL per 100 µL of staining volume. It is recommended that the reagent be titrated for optimal performance for each application. See product image legends for additional information.
Reactivity	Human, Mouse, Rat

Key Properties

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Host	Rabbit
Clonality	Monoclonal
Isotype	Rabbit IgG1k
Clone No.	MSK1T581-A5
Immunogen	A synthetic phospho-peptide corresponding to residues surrounding Thr581 of human phospho MSK1
Purification	Protein A+G
Conjugation	PE

Storage & Handling

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Storage	2-8°C
Form/Appearance	Liquid
Buffer/Preservatives	1X PBS, 0.09% NaN3, 0.2% rAlbumin
Disclaimer	For research use only

Alternative Names

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Ribosomal protein S6 kinase alpha-5, S6K-alpha-5, 90 kDa ribosomal protein S6 kinase 5, Nuclear mitogen- and stress-activated protein kinase 1, RSK-like protein kinase, RSKL, RPS6KA5

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Phospho-MSK1 (Thr581) (A5) rabbit mAb PE conjugate Antibody

Flow cytometric analysis of COS7 cells unstained and untreated (blue) or untreated (red) or treated with TPA + CalA (green) and stained using phospho-MSK1 (T581) PE conjugated antibody MSK1T581-A5. Cat. #orb1946221.

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UniProt

O75582

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No UniProt data available

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Protocol Information

Flow Cytometry

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