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Poly-D-lysine hydrobromide (MW 30000-70000)

SKU: orb1984511

Description

Poly-D-lysine hydrobromide is an orally active peptide agonist of the calcium-sensing receptor (CaSR). It has been shown in vitro to eliminate proteinase K-resistant prion protein from infected neuronal cells, indicating its research application in studying prion disease mechanisms and potential therapeutic strategies.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number27964-99-4
Formula(C6H14N2O2)x.xHBr
SMILES(C6H14N2O2)x.xHBr
TargetCaSR,Others
SolubilityH2O:30 mg/mL

Bioactivity

In Vitro
In rabbits, Poly-D-lysine (PDL) elicits an immune response exclusively at low dosages. The concentration of Poly-D-lysine required to reduce PrPres levels by 50% is approximately 0.8 μg/mL or 50 nM.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Poly-D-lysine HBr (MW 30000-70000), Poly-D-lysine Hydrobromide, PolyDlysine hydrobromide (MW 3000070000), Poly D lysine hydrobromide (MW 30000 70000), CaSR
Quality Guarantee

Quality Guarantee

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Protocol Information

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5 mg
$ 70.00
10 mg
$ 90.00
25 mg
$ 140.00
50 mg
$ 200.00
100 mg
$ 270.00
DispatchUsually dispatched within 5-10 working days
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