Polymyxin B nonapeptide

SKU: orb1679724

Description

Polymyxin B nonapeptide is a cationic cyclic derivative of polymyxin B that disrupts the outer membrane of Gram-negative bacteria by binding to LPS. This permeabilizing action enhances the efficacy of hydrophobic antibiotics in both in vitro and in vivo research models for studying antimicrobial resistance and combination therapies.

Research Area

Infectious Disease & Virology

Images & Validation

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Key Properties

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Target	Antibacterial,Antibiotic
CAS Number	86408-36-8
MW	963.13
Formula	C₄₃H₇₄N₁₄O₁₁
SMILES	C([C@@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCN)C(=O)N[C@@H](CCN)C(=O)N[C@@]([C@@H](C)O)(C(=O)NCC[C@H](NC([C@@H](NC([C@H]([C@@H](C)O)N)=O)CCN)=O)C(=O)N[C@@H](CCN)C(=O)N1)[H])C2=CC=CC=C2

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

123978 ↗

Key Properties

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No computed properties available.

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Protocol Information

Protein Handling and Storage Guide

Protein Handling Guide

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