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PPARγ agonist 17

SKU: orb3029041

Description

PPARγ agonist17 (Compound C1) is an orally active PPARγ agonist. It enhances PPARγ activity, arrests the cell cycle of HT-29 cells at the G2/M phase, inhibits cell migration, and induces apoptosis. PPARγ agonist17 exhibits broad-spectrum antiproliferative activity against cancer cells with relatively low toxicity to normal cells and does not cross the blood-brain barrier.

Research Area

Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number3054652-58-0
MW766.016
FormulaC48H63NO7
SMILESC[C@]12[C@@]3(C)C([C@]4([C@@](C)(CC3)CC[C@@](C(O)=O)(C)C4)[H])=CC(=O)[C@@]1([C@]5(C)[C@@](CC2)(C(C)(C)[C@@H](OC(CC6=CC(NC(COC7=C(C)C=CC(C)=C7)=O)=CC=C6)=O)CC5)[H])[H]
TargetPPAR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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