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Pralidoxime Chloride

SKU: orb1309736

Description

Pralidoxime chloride (2-PAM chloride) is a reactivator of acetylcholinesterase inhibited by organophosphates, making it a critical research tool for studying nerve agent poisoning. Its application extends to both in vitro enzymatic assays and in vivo models for evaluating antidotal efficacy in toxicology and pharmacology research.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number51-15-0
MW172.61
Purity99.96% (May vary between batches)
FormulaC7H9ClN2O
SMILESC[n+]1ccccc1/C=N/O.[Cl-]
TargetCholinesterase (ChE)
SolubilityDMSO:50 mg/mL (289.67 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (11.59 mM)

Bioactivity

In Vitro
The application of pralidoxime allowed the regeneration of an important fraction of inhibited AChE, process which is concentration-dependent.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

2-Pyridinealdoxime methochloride, 2-PAM, 2-PAM (chloride), 2-PAM chloride, 2-PAM Chloride, AchE, diethylparaoxon, Cholinesterase (ChE), organophosphorus, organophosphates, plethymosgraphy, nerve agent, inhibit, Inhibitor, Pralidoxime, Pralidoxime Chloride, reactivator

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    50 mg, 100 mg, 200 mg, 500 mg, 1 g
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Key Properties

No computed properties available.

Protocol Information

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100 mg
$ 70.00
500 mg
$ 110.00
1 g
$ 140.00
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