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Promazine hydrochloride

SKU: orb1224769

Description

Promazine (hydrochloride) is a D2 dopamine receptor antagonist, belongs to the phenothiazine class of antipsychotics, used to treat schizophrenia.(In Vitro):Promazine hydrochloride shows KDs of 25, 190 and 8400 nM at the human norepinephrine transporter, serotonin transporter, and dopamine transporter, respectively.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number53-60-1
MW320.88
Purity>98% (HPLC)
FormulaC17H21ClN2S
SMILESCN(C)CCCN1C2=CC=CC=C2SC3=CC=CC=C31.Cl
Target5-HT Receptor
SolubilitySoluble in DMSO

Bioactivity

In Vitro
Promazine hydrochloride shows KDs of 25, 190 and 8400 nM at the human norepinephrine transporter, serotonin transporter, and dopamine transporter, respectively.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Promazine Hydrochloride | Promazine Hcl | Starazin | Talofen | Promazine monohydrochloride

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  • Promazine hydrochloride [orb1310312]

    99.74% (May vary between batches)

    53-60-1

    320.88

    C17H21ClN2S

    500 mg, 1 ml x 10 mM (in DMSO), 5 g, 200 mg, 1 g
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Protocol Information

Promazine hydrochloride (orb1224769)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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