PROTAC BcI-2/BcI-xI Degrader-1

SKU: orb2564493

Description

PROTACBcI-2/BcI-xI Degrader-1 (15) is a heterobifunctional small molecule that selectively induces the degradation of BcI-2 and BcI-xL proteins. It serves as a chemical tool for studying apoptosis and oncogenesis in both cellular and animal models of cancer research.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	3034200-49-9
MW	1584.35
Formula	C₇₈H₉₄ClF₃N₁₀O₁₂S₄
SMILES	C(NS(=O)(=O)C1=CC(S(C(F)(F)F)(=O)=O)=C(N[C@H](CCN2CCN(C(CCCCCC(N[C@H](C(=O)N3[C@H](C(NCC=4C=C5C(=CC4)C6=C(CCO5)N=CS6)=O)C[C@@H](O)C3)[C@](C)(C)C)=O)=O)CC2)CSC7=CC=CC=C7)C=C1)(=O)C=8C=C9C(N%10[C@@](CN(CC%11=C(CCC(C)(C)C%11)C%12=CC=C(Cl)C=C%12)CC%10)(CO9)[H])=CC8
Target	PROTACs,Bcl-2 Family

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

171714363 ↗

Key Properties

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No computed properties available.

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