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Protease-Activated Receptor-4

SKU: orb1220396

Description

Protease-Activated Receptor-4 is the proteinase-activated receptor-4 (PAR4) agonist with Antiplatelet Therapy.

Research Area

Protein Biochemistry

Images & Validation

Key Properties

CAS Number245443-52-1
MW666.77
Purity>98% (HPLC)
FormulaC33H46N8O7
SMILESNCCCC[C@H](NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
TargetPAR
SolubilityH2O:50 mg/mL (74.99 mM; Need ultrasonic)

Bioactivity

In Vitro
GYPGKF-NH2 significantly reduces the agonistic potency of AYPGKF-NH2 by 25-fold. GYPGKF-NH2 (500 μM) does not cause contraction or relaxation of the guinea pig IAS strips.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

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200 mg
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5 mg
$ 140.00
10 mg
$ 230.00
25 mg
$ 450.00
50 mg
$ 740.00
100 mg
$ 1,080.00