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PX20606

SKU: orb2564340

Description

PX20606 is a potent, orally bioavailable FXR agonist with EC50 values of 220 nM (mouse) and 50 nM (human). It upregulates the tumor suppressor NDRG2, demonstrating hepatoprotective effects and inhibiting hepatocellular carcinoma growth and metastasis in preclinical models.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number1268245-19-7
MW554.85
FormulaC29H22Cl3NO4
SMILESO=C(O)C1=CC=C(C=C1)C2CC2C3=CC=C(OCC=4C(=NOC4C5CC5)C=6C(Cl)=CC=CC6Cl)C=C3Cl
TargetFXR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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    C29H22Cl3NO4

    50 mg, 100 mg, 25 mg
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Key Properties

No computed properties available.

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Protocol Information

PX20606 (orb2564340)

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