Vazyme - Pyrophosphatase, Inorganic (yeast, 0.1 U/μl, GMP Grade)

Pyrophosphatase, Inorganic (inorganic pyrophosphatase) is an enzyme encoded by yeast DNA expressed in the recombinant E. coli , which can catalyze the hydrolysis of inorganic pyrophosphate into orthophosphate: P 2 O 7 4- + H 2 O → 2 HPO 4 2- . Under natural conditions, inorganic pyrophosphatases provide thermodynamic power for the biosynthesis of proteins, DNA, and RNA, and play a role in biotransformation processes such as lipid metabolism, calcium absorption, and bone formation. In nucleic acid amplification tests, this product can hydrolyze inorganic pyrophosphate generated during the reaction to prevent its inhibition against the reaction and promote the translation of the reaction equilibrium towards product generation. This product is GMP grade recombinant Pyrophosphatase, Inorganic (yeast), produced with strict control of host protein, exogenous DNA, RNase and other process-related impurities, as well as microbiological limits and bacterial endotoxins are strictly controlled during the production process. The entire production process does not use or add ampicillin or any raw materials and auxiliary materials of animal origin, and adopts the production and quality management standards in accordance with the GMP norms. The production process and raw and auxiliary materials are traceable, and the product meets the requirements for raw and auxiliary materials in the field of mRNA vaccine production.