Quinpirole Hydrochloride

SKU: orb1708765

Description

Quinpirole Hydrochloride (LY 171555) is a potent and selective dopamine D2/D3 receptor agonist extensively utilized in neuroscience research. It is commonly applied in both in vitro binding assays and in vivo studies to investigate dopaminergic pathways, behaviors, and related disorders in rodent models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	85798-08-9
MW	255.79
Purity	98.00% (May vary between batches)
Formula	C₁₃H₂₂ClN₃
SMILES	Cl.[H][C@]12CCCN(CCC)[C@]1([H])Cc1cn[nH]c1C2
Target	Dopamine Receptor
Solubility	H2O:45 mg/mL (175.93 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.82 mM);DMSO:25 mg/mL (97.74 mM)

Bioactivity

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In Vivo	Examined the functions of the DA D1 receptor (D1R) and DA D2 receptor (D2R) by intrastriatal injection of the D1R agonist SKF38393 and the D2R agonist quinpirole. At threshold doses, quinpirole (1.0 μg/site) produce a dose-dependent increase in locomotor activity compared to vehicle injection，in 6-hydroxydopamine (6-OHDA)-lesioned and control rat. Read more...

Storage & Handling

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Storage	store at low temperature,keep away from direct sunlight \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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(-)-LY 171555, DopamineReceptor, Dopamine Receptor, D3 receptor, D2 receptor, D2, LY171555, LY-171555, LY 171555, LY 171555, Quinpirole Hydrochloride

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Compound Identifiers

PubChem CID

55397 ↗

Key Properties

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No computed properties available.

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