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Quinpirole Hydrochloride

SKU: orb1708765

Description

Quinpirole Hydrochloride (LY 171555) is a potent and selective dopamine D2/D3 receptor agonist extensively utilized in neuroscience research. It is commonly applied in both in vitro binding assays and in vivo studies to investigate dopaminergic pathways, behaviors, and related disorders in rodent models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number85798-08-9
MW255.79
Purity98.00% (May vary between batches)
FormulaC13H22ClN3
SMILESCl.[H][C@]12CCCN(CCC)[C@]1([H])Cc1cn[nH]c1C2
TargetDopamine Receptor
SolubilityH2O:45 mg/mL (175.93 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.82 mM);DMSO:25 mg/mL (97.74 mM)

Bioactivity

In Vivo
Examined the functions of the DA D1 receptor (D1R) and DA D2 receptor (D2R) by intrastriatal injection of the D1R agonist SKF38393 and the D2R agonist quinpirole. At threshold doses, quinpirole (1.0 μg/site) produce a dose-dependent increase in locomotor activity compared to vehicle injection,in 6-hydroxydopamine (6-OHDA)-lesioned and control rat.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

(-)-LY 171555, DopamineReceptor, Dopamine Receptor, D3 receptor, D2 receptor, D2, LY171555, LY-171555, LY 171555, LY 171555, Quinpirole Hydrochloride

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Key Properties

No computed properties available.

Protocol Information

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1 mg
$ 140.00
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