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(R)-Doxazosin

SKU: orb3135857

Description

(R)-Doxazosin ((R)-UK 33274) is an isomer of Doxazosin, a selective oral a1-adrenoceptor agonist. Doxazosin is utilized for systemic antihypertensive and ocular hypotensive purposes. It achieves its antihypertensive effect by selectively blocking postsynaptic a1 receptors, reducing total peripheral resistance without impacting cardiac output. Doxazosin significantly lowers both standing and supine blood pressure.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number70918-17-1
MW451.48
FormulaC23H25N5O5
SMILESNC=1C2=C(N=C(N1)N3CCN(C(=O)[C@@H]4OC=5C(OC4)=CC=CC5)CC3)C=C(OC)C(OC)=C2
TargetAdrenergic Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information