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SAG

SKU: orb2567305

Description

(Rac)-SAG is a potent and selective Smoothened (Smo) agonist (EC₅₀ = 3 nM) that activates Hedgehog signaling. It is widely used in biochemical and cellular assays to study pathway mechanisms and has been applied in vivo to explore tissue regeneration and oncogenesis models.

Research Area

Neuroscience

Images & Validation

Key Properties

CAS Number364590-63-6
MW490.07
Purity>98%
FormulaC28H28ClN3OS
SMILESN(C(=O)C1=C(Cl)C=2C(S1)=CC=CC2)(CC3=CC(=CC=C3)C=4C=CN=CC4)C5CCC(NC)CC5
TargetGPCR
SolubilitySoluble in DMSO (up to 20 mg/ml), in DMF (up to 20 mg/ml) or in Ethanol (up to 20 mg/ml).

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Smoothened Agonist

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Key Properties

No computed properties available.

Protocol Information

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1 mg
$ 150.00
5 mg
$ 240.00
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