RAGE antagonist peptide

SKU: orb1679416

Description

This small molecule RAGE antagonist inhibits activation by ligands including S100P, S100A4, and HMGB-1. It suppresses RAGE-mediated NF-κB activity and cell growth in vitro, and demonstrates efficacy in reducing tumor growth and metastasis in rat glioma and murine exposure models, supporting research in oncology and inflammation.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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Target	Beta Amyloid
CAS Number	1092460-91-7
MW	1272.56
Formula	C₅₇H₁₀₁N₁₃O₁₇S
SMILES	[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(N)=O)=O)CCC(O)=O)=O)CCCCN)=O)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCC(O)=O)NC(C)=O)=O)CC(C)C)=O)CCCCN)=O)[C@H](C)C)=O)CC(C)C)=O)CCSC)=O)CCC(O)=O

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

127021052 ↗

Key Properties

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No computed properties available.

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Protocol Information

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