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Human HER3
SKU: orb2993801
Description
Images & Validation
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Key Properties
−| Expression System | Human Cells |
|---|---|
| Biological Origin | Human |
| Biological Activity | BLI: Loaded Human NRG1Beta (245AA)(Cat#orb3002365) on APS Biosensor, can bind Human HER3-mFc(Cat#orb2993801) with an affinity constant of 3.6 nM as determined in BLI assay. Loaded Human NRG1Beta (246AA)(Cat#CH84) on APS Biosensor, can bind Human HER3-mFc(Cat#orb2993801) with an affinity constant of 4.3 nM as determined in BLI assay. |
| Tag | C-mFc |
| Molecular Weight | Predicted: 95.1 KDa. Observed: 120-135 KDa, reducing conditions |
| Expression Region | Ser20-Thr643 |
| Purity | SDS-PAGE: Greater than 95% as determined by reducing SDS-PAGE. |
| Endotoxins | < 1 EU/µg as determined by LAL test. |
| Conjugation | Unconjugated |
Storage & Handling
−| Storage | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
|---|---|
| Form/Appearance | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Expiration Date | 6 months from date of receipt. |
| Disclaimer | For research use only |
Alternative Names
−Proto-oncogene-like protein c-ErbB-3; Tyrosine kinase-type cell surface receptor HER3; ERBB3; HER3
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Human HER3 (orb2993801)
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