RE(EDANS)EVNLDAEFK(DABCYL)R

SKU: orb2277353

Description

This double-labeled peptide substrate, containing EDANS and DABCYL fluorophores, is designed for sensitive quantification of BACE1 activity. Its fluorescence intensity at 528/360 nm (ex/em) directly correlates with enzymatic cleavage, making it a key tool for in vitro inhibitor screening and Alzheimer's disease-related research.

Research Area

Neuroscience

Images & Validation

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Key Properties

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Target	Beta-Secretase
Molecular Weight	2005.22
CAS Number	310427-94-2
Formula	C₉₁H₁₂₉N₂₅O₂₅S
SMILES	N(CCNC(CC[C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CCCCNC(=O)C2=CC=C(N=NC3=CC=C(N(C)C)C=C3)C=C2)=O)=O)CCC(O)=O)=O)C)=O)CC(O)=O)=O)CC(C)C)=O)CC(N)=O)=O)C(C)C)=O)CCC(O)=O)=O)NC([C@H](CCCNC(=N)N)N)=O)=O)C=4C5=C(C(S(=O)(=O)O)=CC=C5)C=CC4

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

102601034 ↗

Key Properties

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No computed properties available.

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