Regdanvimab Antibody

SKU: orb1980592

Description

Regdanvimab (CT-P59) is a humanized monoclonal antibody that neutralizes SARS-CoV-2 by binding to the viral spike protein's receptor-binding domain, blocking ACE2-mediated cellular entry. It has demonstrated antiviral efficacy in both in vitro studies and in vivo animal models of COVID-19 infection.

Research Area

Infectious Disease & Virology, Metabolism Research

Images & Validation

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Key Properties

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CAS Number	2444308-95-4
MW	146.22 kDa
Purity	95.00%
Target	RAAS,SARS-CoV,Angiotensin-converting Enzyme (ACE)

Bioactivity

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In Vivo	Treatment with Regdanvimab (5, 20, 40, and 80 mg/kg, intrabitoneally injected) relieved respiratory symptoms and eliminated the virus in mice infected with the SARS-CoV-2 variant. Read more...
In Vitro	Regdanvimab neutralizes the gamma, Delta, Epsilon, and Kappa variants of SARS-CoV-2 in cells.

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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T-P59, IN006, IN-006, CTP59, CT-P59

Quality Guarantee

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Gene Symbol

RAAS,SARS-CoV,Angiotensin-converting Enzyme (ACE)

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