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Relenopride

SKU: orb2281164

Description

Relenopride (YKP-10811) is a selective serotonin 5-HT4 receptor agonist utilized in gastrointestinal research. It enhances intestinal motility and is applied in both in vitro and in vivo experimental models for studying functional gut disorders like constipation and irritable bowel syndrome.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1221416-43-8
MW492.97
Purity99.76%
FormulaC24H30ClFN4O4
SMILESC(NCC1CCN(CC[C@H](OC(N)=O)C2=CC=C(F)C=C2)CC1)(=O)C3=C(OC)C=C(N)C(Cl)=C3
Target5-HT Receptor
SolubilityH2O:30 mg/mL (60.86 mM);DMSO:80 mg/mL (162.28 mM)

Bioactivity

Target IC50
5-HT2B Receptor:31 nM (Ki)|5-HT2B Receptor:2.1 μM|5-HT4 Receptor:4.96 nM (Ki)|5-HT2A Receptor:600 nM (Ki)
In Vitro
Relenopride hydrochloride exhibits antagonist activity at the 5-HT2B receptor with an IC50 of 2.1 μM, while it shows no significant activity at the 5-HT2A receptor up to 10 μM.

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

5HT Receptor, 5HTReceptor, 5-HT4, SKL-IBS, YKP 10811

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    C24H31Cl2FN4O4

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Key Properties

No computed properties available.

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Relenopride (orb2281164)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

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1 mg
¥ 1,560.00
5 mg
¥ 2,990.00
10 mg
¥ 4,290.00
25 mg
¥ 6,630.00
DispatchUsually dispatched within 5-10 working days
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