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Rezatapopt

SKU: orb1943475

Description

Rezatapopt (PC14586) is a selective small molecule reactivator of the p53 Y220C mutant, restoring its wild-type conformation and transcriptional function. This compound is utilized in preclinical research for studying locally advanced or metastatic solid tumors, with demonstrated activity in both in vitro and in vivo models.

Research Area

Cell Biology

Images & Validation

Key Properties

CAS Number2636846-41-6
MW545.57
Purity99.72% (May vary between batches)
FormulaC28H31F4N5O2
SMILESN(C1=C2C(N(CC(F)(F)F)C(C#CCNC3=C(OC)C=C(C(NC)=O)C=C3)=C2)=CC=C1)[C@H]4[C@@H](F)CN(C)CC4
TargetMDM-2/p53,Others,p53
SolubilityDMSO:80 mg/mL (146.64 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

p53, PC14586

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 130.00
5 mg
$ 210.00
1 ml x 10 mM (in DMSO)
$ 240.00
10 mg
$ 310.00
25 mg
$ 520.00
50 mg
$ 730.00
100 mg
$ 1,040.00
DispatchUsually dispatched within 5-10 working days
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