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RNAse L RIBOTAC

SKU: orb2945632

Description

Compound C64 is a ribonuclease-targeting chimera (RIBOTAC) that recruits RNase L to degrade viral RNA by selectively binding the SL5 four-way junction in the SARS-CoV-2 5' UTR. This mechanism inhibits viral replication, as demonstrated in cellular models like pulmonary epithelial cells, supporting its investigation as a potential antiviral research tool.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

MW1073.18
FormulaC55H60N8O13S
SMILESCCOC(=O)C1=C(/C(=C/C2=CC(=C(C=C2)OCCOCCN3C=C(N=N3)COCCOCCOCCOCCOC4=CC5=NC(=CN5C=C4)C6=CC7=C(C=C(C=C7)N8CCNCC8)OC6=O)O)/SC1=NC9=CC=CC=C9)O
TargetPROTACs

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information