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RORγt inverse agonist 14

SKU: orb1944820

Description

The potent and selective RORγt inverse agonist 14 (8e) demonstrates oral activity with an EC50 of 2.5 nM. It is a valuable research tool for investigating Th17-driven pathologies, showing anti-inflammatory effects in both cellular assays and in vivo models of rheumatoid arthritis and psoriasis.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number2672496-70-5
MW678.61
FormulaC26H26F8N2O6S2
TargetROR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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RORγt inverse agonist 14 (orb1944820)

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