RORγt inverse agonist 33

SKU: orb2945455

Description

RORγt inverse agonist 33 (compound (R)-D4) is an orally active small molecule with an IC50 of 21 nM. It is a valuable research tool for investigating Th17 cell biology and has demonstrated efficacy in preclinical models of autoimmune diseases, including rheumatoid arthritis.

Research Area

Metabolism Research

Images & Validation

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Key Properties

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MW	487.651
Formula	C₂₇H₃₇NO₅S
SMILES	CC[C@@H]1CCC2=C(N1S(=O)(=O)C3=CC(=C(C=C3)COC4CCOCC4)CO)C=CC(=C2)C(C)C
Target	ROR

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

172676925 ↗

Key Properties

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No computed properties available.

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