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RORγt inverse agonist 33

SKU: orb2945455

Description

RORγt inverse agonist 33 (compound (R)-D4) is an orally active small molecule with an IC50 of 21 nM. It is a valuable research tool for investigating Th17 cell biology and has demonstrated efficacy in preclinical models of autoimmune diseases, including rheumatoid arthritis.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

Key Properties

MW487.651
FormulaC27H37NO5S
SMILESCC[C@@H]1CCC2=C(N1S(=O)(=O)C3=CC(=C(C=C3)COC4CCOCC4)CO)C=CC(=C2)C(C)C
TargetROR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information