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RORγt inverse agonist 34

SKU: orb2945800

Description

Compound 5a (34) is a potent RORγt inverse agonist with an IC50 of 94 nM against the ligand-binding domain. It is a valuable research tool for investigating Th17-driven pathologies, such as psoriasis, in both cellular and animal model studies.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2247604-77-7
MW531.709
FormulaC31H37N3O3S
SMILESO=C1C2=CC=C(C=C2CCC1)NC3=CC=C4C(=C3)CCCN4S(=O)(=O)N(C)CC5=CC=C(C=C5)C(C)(C)C
TargetROR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information