S-Nitroso-N-acetyl-DL-penicillamine

SKU: orb1219697

Description

S-Nitroso-N-acetyl-DL-penicillamine acts as a stable inhibitor of platelet aggregation, is a nitric oxide donor and . S-Nitroso-N-acetyl-DL-penicillamine (10 mM; 8 hours) after 6 hours under normoxic conditions by releasing nitric oxide (NO)induces toxicity of about 80% . S-Nitroso-N-acetyl-DL-penicillamine has a half-time about 6 hours in in isolated rat ventricular myocytes. S-Nitroso-N-acetyl-DL-penicillamine (100 μM; 30 minutes) causes sustained decrease in the basal pHi in isolated rat ventricular myocytes.

Research Area

Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	67776-06-1
MW	220.25
Purity	>98% (HPLC)
Formula	C₇H₁₂N₂O₄S
SMILES	CC(=O)NC(C(O)=O)C(C)(C)SN=O
Target	NOS
Solubility	DMSO:250 mg/mL (1135.07 mM; Need ultrasonic)

Bioactivity

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In Vitro	Cell Viability Assay Cell line: Rat liver sinusoidal endothelial cells. Concentration: 2 mM, 5 mM, 10 mM. Incubation time: 2 hours, 4 hours, 6 hours, 8 hours. Result: Exhibited cytotoxicity against cultivated endothelial cells. Read more...

Storage & Handling

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Storage	Storage temperature: -20°C. Stability: ≥ 2 years
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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SNAP

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Gene Symbol

NOS

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