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S-Nitroso-N-acetyl-DL-penicillamine

SKU: orb1219697

Description

S-Nitroso-N-acetyl-DL-penicillamine acts as a stable inhibitor of platelet aggregation, is a nitric oxide donor and . S-Nitroso-N-acetyl-DL-penicillamine (10 mM; 8 hours) after 6 hours under normoxic conditions by releasing nitric oxide (NO)induces toxicity of about 80% . S-Nitroso-N-acetyl-DL-penicillamine has a half-time about 6 hours in in isolated rat ventricular myocytes. S-Nitroso-N-acetyl-DL-penicillamine (100 μM; 30 minutes) causes sustained decrease in the basal pHi in isolated rat ventricular myocytes.

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Key Properties

CAS Number67776-06-1
MW220.25
Purity>98% (HPLC)
FormulaC7H12N2O4S
SMILESCC(=O)NC(C(O)=O)C(C)(C)SN=O
TargetNOS
SolubilityDMSO:250 mg/mL (1135.07 mM; Need ultrasonic)

Bioactivity

In Vitro
Cell Viability Assay Cell line: Rat liver sinusoidal endothelial cells. Concentration: 2 mM, 5 mM, 10 mM. Incubation time: 2 hours, 4 hours, 6 hours, 8 hours. Result: Exhibited cytotoxicity against cultivated endothelial cells.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

SNAP

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S-Nitroso-N-acetyl-DL-penicillamine (orb1219697)

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