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(S)-Sunvozertinib

SKU: orb1298200

Description

(S)-Sunvozertinib

Research Area

Cardiovascular Research, Signal Transduction

Images & Validation

Key Properties

CAS Number2370013-49-1
MW584.08
Purity99.69%
FormulaC29H35ClFN7O3
SMILESCOc1cc(N2CC[C@@H](C2)N(C)C)c(NC(=O)C=C)cc1Nc1nccc(Nc2cc(Cl)c(F)cc2C(C)(C)O)n1
TargetBTK,HER,EGFR
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.42 mM);DMSO:55 mg/mL (94.17 mM)

Bioactivity

Target IC50
EGFR (exon 20 NPH):51.2 nM IC50 |EGFR (L858R/T790M):1 nM IC50 |HER2 exon20 YVMA insertion:21.2 nM IC50 |EGFR (exon 20 ASV insertion):51.9 nM IC50

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
DisclaimerFor research use only

Alternative Names

Btk, Bruton tyrosine kinase, (S) Sunvozertinib, (S)-DZD9008, (S)Sunvozertinib, (S)-Sunvozertinib, DZD 9008, DZD9008, DZD-9008, breast cancer, Epidermal growth factor receptor, ErbB-1, EGFR, HER2, HER1, Her2, Inhibitor, mutant forms of ErbB, inhibit, lung, N-[5-[[4-[5-Chloro-4-fluoro-2-(2-hydroxypropan-2-yl)anilino]pyrimidin-2-yl]amino]-2-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]-4-methoxyphenyl]prop-2-enamide, Sunvozertinib
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Key Properties

No computed properties available.

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Protocol Information

(S)-Sunvozertinib (orb1298200)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
¥ 1,300.00
5 mg
¥ 2,340.00
1 ml x 10 mM (in DMSO)
¥ 2,860.00
10 mg
¥ 3,510.00
25 mg
¥ 6,370.00
50 mg
¥ 9,100.00
100 mg
¥ 12,740.00
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