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(S)-Willardiine

SKU: orb1708123

Description

(S)-Willardiine, a natural compound found in Acacia and Mimosa seeds, is a selective agonist for AMPA and kainate receptors with an EC50 of 44.8 µM. It is widely used in neuroscience research to study excitatory synaptic transmission, receptor pharmacology, and glutamatergic signaling pathways in both in vitro and in vivo experimental models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number21416-43-3
MW199.16
Purity99.85%
FormulaC7H9N3O4
SMILESN[C@@H](Cn1ccc(=O)[nH]c1=O)C(O)=O
TargetiGluR
SolubilityDMSO:Insoluble

Bioactivity

Target IC50
AMPA/kainate receptor:44.8 μM(EC50)
In Vitro
(S)-Willardiine produces rapidly but incompletely desensitizing responses. Ca2+(1.8 mM) inhibits the currents induced by willardiine(100 μM) by 50% .

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

L-willardiine, Kainate receptor, AMPAR, (-)-Willardiine, Willardiine
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Key Properties

No computed properties available.

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Protocol Information

(S)-Willardiine (orb1708123)

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5 mg
¥ 1,170.00
10 mg
¥ 1,560.00
50 mg
¥ 5,070.00
100 mg
¥ 7,280.00
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