Salbutamol

SKU: orb1225851

Description

Salbutamol is a short-acting β2-adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthma and chronic obstructive pulmonary disease (COPD).

Research Area

Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	18559-94-9
MW	239.31
Purity	>98% (HPLC)
Formula	C₁₃H₂₁NO₃
SMILES	CC(C)(C)NCC(O)C1=CC(CO)=C(O)C=C1
Target	Adrenergic Receptor
Solubility	DMSO: 10 mM

Bioactivity

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In Vivo	Animal model: STZ induced diabetic rats. Dosage: 6 mg/kg. Administration: p.o. Result: Enhanced muscle grip strength, coordination, and antioxidant levels. Reduced proinflammatory markers and oxidative stress. Reduced serum muscle biomarkers. Increased testosterone, restored lipidemic levels, and improved muscle cellular architecture.
In Vitro	Western blot analysis. Cell line: MGC803, SGC7901. Concentration: 16 μM. Incubation time: 24 h. Result: Increased β2-AR and ERK levels. Upregulated mesenchymal markers, CDH2 (N-cadherin) and Snail expression, and decreased the expression of epithelial marker CDH1 (E-cadherin).

Storage & Handling

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Storage	Storage temperature: -20°C. Stability: ≥ 2 years
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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AH 3365 | (±)-Salbutamol | DL-Salbutamol

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Gene Symbol

Adrenergic Receptor

Protocol Information

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Dynamic Range:	0.1 ppb-8.1 ppb
Sensitivity:	0.1 ppb.

Applications:	ELISA
Species/Host:	Rabbit
Clonality:	Polyclonal
Conjugation:	Unconjugated

Salbutamol

Description

Research Area

Images & Validation

Key Properties

Bioactivity

Storage & Handling

Alternative Names

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