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SAR247799

SKU: orb2944227

Description

SAR247799 (S1P1 agonist 3) is a selective and G-protein-biased S1P1 agonist that activates downstream G-protein signaling pathways more preferentially than β-blocker proteins and internalized signaling pathways, activates S1P 1 on endothelial cells without causing receptor desensitization, and protects the endothelium without affecting lymphocyte populations, and can be used to study type 2 diabetes, endothelial dysfunction and vascular hyperpermeability.

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Key Properties

CAS Number1315311-14-8
MW425.82
FormulaC21H16ClN3O5
SMILESO=C(O)COC=1C(=CC(=CC1C)C2=NC3=CN=C(N=C3O2)OC=4C=CC=C(Cl)C4)C
TargetS1P Receptor,LPL Receptor

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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SAR247799 (orb2944227)

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