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SARS-CoV-2 3CLpro-IN-33

SKU: orb3173549

Description

SARS-CoV-2 3CLpro-IN-33 (Compound 16) is an orally active inhibitor of the SARS-CoV-2 3CL protease, with an IC50 value of 1.5 nM. It demonstrates excellent antiviral activity against SARS-CoV-2 in an HEK293T-AT cell model, with an EC50 value of 0.017 μM. SARS-CoV-2 3CLpro-IN-33 is applicable in COVID-19 infection research.

Images & Validation

Key Properties

CAS Number2920182-91-6
MW578.94
FormulaC28H18ClF3N6O3
SMILESN#CC1=CC=C(Cl)C(=C1)C=2C=C3C(C(=O)N(C(=O)N3CC4=CC(F)=C(F)C(F)=C4)CC=5N=CN(N5)C)=C6OCCC62
TargetSARS-CoV

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information