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SARS-CoV-2-IN-81

SKU: orb3133524

Description

SARS-CoV-2-IN-81 (compound 12e) is an effective AAK1 inhibitor with an IC50 value of 9.38 nM. It demonstrates antiviral activity against SARS-CoV-2 by reducing AAK1-induced phosphorylation of threonine 156 on AP2M1 and disrupting the direct interaction between AP2M1 and ACE2, ultimately inhibiting SARS-CoV-2 infection.

Research Area

Infectious Disease & Virology, Neuroscience

Images & Validation

Key Properties

FormulaC25H20N4O2
TargetAAK1 (AP2 associated kinase 1),SARS-CoV

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information