SARS-CoV-2 PLpro-IN-2

SKU: orb3173416

Description

SARS-CoV-2 PLpro-IN-2 (Compound 12) is a highly selective inhibitor of the SARS-CoV-2 papain-like protease (PLpro) with an IC50 of 0.06 μM. It effectively inhibits viral replication and immune evasion. In HeLa-ACE2 cells, SARS-CoV-2 PLpro-IN-2 demonstrates antiviral activity with an EC50 of 2.9 μM. This compound shows potential for use in COVID-19 research.

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Key Properties

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CAS Number	1581755-42-1
MW	406.95
Formula	C₂₅H₂₇ClN₂O
SMILES	[C@@H](C)(C=1C2=C(C=CC1)C=CC=C2)N3CCC(C(NCC4=CC=C(Cl)C=C4)=O)CC3
Target	SARS-CoV,Virus Protease

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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SARS-CoV,Virus Protease

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