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SCH 221510

SKU: orb1704079

Description

SCH 221510 is a potent and selective orally bioavailable NOP receptor agonist (Ki=0.3 nM, EC50=12 nM). It exhibits anxiolytic-like effects in preclinical models and is a valuable research tool for investigating the N/OFQ-NOP receptor system in neurological disorders, including anxiety and depression.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number322473-89-2
MW397.55
Purity99.10% (May vary between batches)
FormulaC28H31NO
SMILESC(N1[C@@]2(C[C@@](O)(C[C@]1(CC2)[H])C3=CC=CC=C3)[H])(C4=C(C)C=CC=C4)C5=C(C)C=CC=C5
TargetOpioid Receptor
SolubilityDMSO:50 mg/mL (125.77 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.03 mM)

Bioactivity

Target IC50
NOP:12 nM( EC50)|NOP:0.3 nM(Ki )

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Opioid Receptor, OpioidReceptor, NOP receptor, SCH221510, SCH-221510, SCH 221510
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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1 mg
$ 120.00
5 mg
$ 220.00
10 mg
$ 320.00
25 mg
$ 610.00
50 mg
$ 940.00
100 mg
$ 1,490.00
200 mg
$ 1,990.00
DispatchUsually dispatched within 3-5 working days
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