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Serotonin hydrochloride

SKU: orb1306100

Description

Serotonin hydrochloride is an endogenous monoamine neurotransmitter that acts as an agonist at 5-HT receptors and inhibits catechol O-methyltransferase (COMT) with a Ki of 44 µM. It is widely used in neuroscience research to study serotonergic signaling, neurotransmission, and receptor pharmacology in both cellular and animal models.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number153-98-0
MW212.676
Purity98.00% (May vary between batches)
FormulaC10H13ClN2O
SMILESCl.NCCc1c[nH]c2ccc(O)cc12
TargetTransferase,Endogenous Metabolite,5-HT Receptor
SolubilityDMSO:128 mg/mL (601.85 mM);H2O:21.3 mg/mL (100.15 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (18.81 mM)

Bioactivity

Target IC50
COMT:44 μM(Ki)
In Vivo
The role of serotonin in the regulation of larval Aedes aegypti hemolymph composition is investigated in vivo using two reuptake inhibitors (SSRIs), alaproclate HCl and 6-nitroquipazine maleate, and the receptor antagonist methiothepin mesylate.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Endogenous Metabolite, EndogenousMetabolite, Inhibitor, inhibit, 5-HT Receptor, 5HT Receptor, 5-HT HCl, 5-HT hydrochloride, 5-HT Hydrochloride, 5-HT, 5HTReceptor, 5-hydroxytryptamine Receptor, 5-Hydroxytryptamine, 5-Hydroxytryptamine Hydrochloride, 5-Hydroxytryptamine hydrochloride, COMT, Serotonin, Serotonin Receptor, Serotonin hydrochloride, Serotonin Hydrochloride, Serotonin HCl

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Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

25 mg
$ 70.00
1 ml x 10 mM (in DMSO)
$ 90.00
50 mg
$ 90.00
100 mg
$ 100.00
200 mg
$ 120.00
DispatchUsually dispatched within 3-5 working days
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