Sheep Human Factor I Antibody

SKU: orb21240

Description

Precipitating polyclonal sheep antiserum to human factor I. Factor I is a serine protease composed of two disulphide-linked chains. The protein has a molecular weight of 88.000 and its mean concentration in human plasma is 35 mg/ml. It is involved in the regulation of the C3/C5 convertase of either pathway. Using C4-binding protein or factor H splits the a chains of C4b or C3b respectively, which includes their roles in the C3/C5 convertases. It has been isolated as a homogenous protein for use in the antiserum production. Freund's complete adjuvant is used in the first step of the immunization procedure.

Research Area

Epigenetics, Immunology, Infectious Diseases

Images & Validation

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Reactivity	Human

Key Properties

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Antibody Type	Primary Antibody
Host	Sheep
Clonality	Polyclonal
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Form/Appearance	Delipidated, heat inactivated, lyophilized, stable IgG fraction. No preservative added. Total protein and IgG concentration are comparable to those of pooled normal sheep serum. No foreign proteins added.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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UniProt

P05156

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No UniProt data available

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