SKF 81297 hydrobromide

SKU: orb1704060

Description

SKF 81297 hydrobromide is a potent and selective dopamine D1/D5 receptor agonist (Ki = 1.9 nM). It is extensively utilized in neuroscience research to investigate dopaminergic pathways in models of cognitive function, motor control, and Parkinson's disease, in both in vitro and in vivo experimental systems.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	67287-39-2
MW	370.67
Purity	99.52% (May vary between batches)
Formula	C₁₆H₁₇BrClNO₂
SMILES	Br.ClC=1C(O)=C(O)C=C2C1CCNCC2C=3C=CC=CC3
Target	Dopamine Receptor
Solubility	10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (6.74 mM);DMF:20 mg/mL (53.96 mM);Ethanol:1 mg/mL (2.7 mM);DMSO:20 mg/mL (53.96 mM)

Bioactivity

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In Vivo	SKF 81297 hydrobromide (0.05-0.3 mg/kg, intramuscularly) can stimulate MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) to impair motor behavior in monkeys. Read more...

Storage & Handling

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Storage	store under nitrogen,store at low temperature \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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SKF81297 hydrobromide, SKF-81297 Hydrobromide

Quality Guarantee

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Compound Identifiers

PubChem CID

11957706 ↗

Key Properties

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No computed properties available.

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