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SORT-PGRN interaction inhibitor 3

SKU: orb1944342

Description

Compound 13 is a potent small molecule inhibitor of the SORT1-PGRN interaction with an IC50 of 0.17 µM. It is a valuable research tool for investigating the role of this pathway in neurodegenerative disease models, including frontotemporal dementia, in both cellular and animal studies.

Research Area

Neuroscience; Pharmacology & Drug Discovery, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2691846-87-2
MW332.22
FormulaC15H19Cl2NO3
SMILESC(N[C@@H](CCC(C)(C)C)C(O)=O)(=O)C1=CC(Cl)=CC(Cl)=C1
TargetNeurotensin Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information