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SPL-707

SKU: orb1706610

Description

SPL-707 is a potent and selective small molecule inhibitor of signal peptide peptidase-like 2a (SPPL2a), exhibiting an IC50 of 80 nM. This inhibitor is a valuable research tool for investigating the role of SPPL2a in intramembrane proteolysis, with applications in immunological and neurodegenerative disease research using both cellular and animal models.

Research Area

Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number2195361-33-0
MW505.54
FormulaC27H28FN5O4
SMILESCc1ncc(F)cc1NC(=O)C[C@@H](C1CC1)C(=O)N[C@H]1c2ccccc2C(=O)N2CC3(CC3)CN2C1=O
TargetOthers

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information