SR 2640 hydrochloride

SKU: orb1704039

Description

SR 2640 hydrochloride is a selective, competitive antagonist of the cysteinyl leukotrienes LTD4 and LTE4. It serves as a valuable pharmacological tool for investigating the role of these mediators in airway pathophysiology, applicable in both in vitro receptor studies and in vivo models of asthma.

Research Area

Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	146662-42-2
MW	406.86
Purity	99.31% (May vary between batches)
Formula	C₂₃H₁₉ClN₂O₃
SMILES	Cl.OC(=O)c1ccccc1Nc1cccc(OCc2ccc3ccccc3n2)c1
Target	Leukotriene Receptor
Solubility	DMSO:225 mg/mL (553.02 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (12.29 mM)

Bioactivity

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In Vivo	In Guinea pigs, intravenous injection of SR2640 (1 mg/kg) prevents the contractile responses of the ileum and trachea to leukotriene D4 and E4.

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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LeukotrieneReceptor, leukotriene receptor, Leukotriene Receptor, SR2640 Hydrochloride, SR-2640 Hydrochloride, SR 2640 hydrochloride, SR 2640 Hydrochloride

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Compound Identifiers

PubChem CID

45073453 ↗

Key Properties

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No computed properties available.

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