(S,R,S)-AHPC-Me dihydrochloride

SKU: orb1707973

Description

(S,R,S)-AHPC-Me dihydrochloride (VHL Ligand 2) is a key component for constructing VHL-based PROTAC degraders like ARV-771. This potent VHL-recruiting ligand enables the targeted degradation of proteins, such as BET proteins, which has been demonstrated in cellular studies for castration-resistant prostate cancer research.

Research Area

Pharmacology & Drug Discovery

Images & Validation

−

Key Properties

−

MW	517.51
Formula	C₂₃H₃₄Cl₂N₄O₃S
SMILES	N[C@@H](C(C)(C)C)C(N1[C@H](C(N[C@@H](C)C2=CC=C(C3=C(C)N=CS3)C=C2)=O)C[C@@H](O)C1)=O.Cl.Cl
Target	Ligands for E3 Ligase,E3 Ligase Ligand-Linker Conjugates,Others

Storage & Handling

−

Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Compound Identifiers

PubChem CID

137319712 ↗

Key Properties

−

No computed properties available.

Documents Download

Datasheet

Product Information

Download

Request a Document

Protocol Information

Find More Protocols