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ST171

SKU: orb3136000

Description

ST171 is a dual-action 5-HT1AR agonist with a Ki of 0.41 nM. It selectively activates the Gi/o signaling pathway and inhibits cAMP accumulation mediated by 5-HT1AR, without Gs activation and with minimal β-arrestin recruitment. ST171 reduces hypersensitivity in mouse models of chronic neuropathic and inflammatory pain and is applicable for pain research.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

Target5-HT Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information