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STAT3-IN-44

SKU: orb3136041

Description

STAT3-IN-44 is a potent STAT3 inhibitor with IC50 values of 1.84 μM (C6 cells) and 4.81 μM (A549 cells). It inhibits the phosphorylation of STAT3, downregulates Bcl-2 expression, and upregulates Caspase-3 expression, thereby promoting late-stage apoptosis. STAT3-IN-44 effectively suppresses tumor cell proliferation and migration and is applicable in research on cancers such as glioma and lung cancer.

Research Area

Cancer Biology, Cell Biology, Protein Biochemistry, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

TargetCaspase,STAT,Bcl-2 Family,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

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Protocol Information