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STING agonist-43

SKU: orb3135672

Description

STINGagonist-43 (Compound 67) is a selective STING agonist with an EC50 of 20.53 μM. It selectively enhances the cGAMP-dependent STING pathway activation by modulating STING oligomerization. STINGagonist-43 demonstrates antitumor activity in a B16.F10 mouse melanoma model and can be utilized in cancer immunotherapy research.

Research Area

Immunology & Inflammation, Pharmacology & Drug Discovery; Cell Biology

Images & Validation

Key Properties

CAS Number2882097-31-4
MW353.41
FormulaC21H23NO4
SMILESO=C(OCC)CN1C2=CC=C(C=C2C(=O)C3=CC(OC)=C(C(=C31)C)C)C
TargetSTING

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information